Search Result

Search Results for " fibronectin 1 "

Targets

Compounds

Natural Products

1785

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1526L1	Fibronectin CS1 Peptide acetate		Others
	CS1 peptide is present within type III homology connecting segment (IIICS) as well as C-274 (cell-binding domain). Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in sp...		Others
TP1530L	YRGDS Fibronectin Fragment acetate	YRGDS Fibronectin Fragment acetate(134282-68-1 free base)	Others
	YRGDS Fibronectin Fragment acetate (YRGDS Fibronectin Fragment acetate (134282-68-1 free base))(134282-68-1 free base) is a fibronectin fragment acetate, an adhesion peptide that displays strong binding affinity to throm...		Others
TP1526	Fibronectin CS1 Peptide
	he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively i...
T82403	Fibronectin Type III Connecting Segment Fragment 1-25
	Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide implicated in melanoma cell adhesion and critical for the development of the chicken peripheral nervous system [1] [2].
T61389	TGFβ1-IN-1		TGF-beta/Smad
	TGFβ1-IN-1 is an orally active TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrotic markers (α-SMA and fibronectin) and can be used for the study of cancer and autoimmune diseases.		TGF-beta/Smad
T37047	12(S)-HETE
	12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. [1] It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1μM181M.[2][3]
T69203	HMR1031
	HMR1031 is a potent and specific integrin α4ß1 or very late antigen 4 (VLA-4) receptor antagonist which binds to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin.
T76286	REDV
	REDV is a minimal active sequence found in the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin, critical for mediating adhesion to the IIICS region of plasma fibronectin th...
T78029	REDV TFA		Integrin
	REDV TFA, the minimal active sequence of the CS5 site in the alternatively spliced type III connecting segment (IIICS) of fibronectin, mediates adhesion to the IIICS region of plasma fibronectin through binding with the ...		Integrin
T36930	Palmitoyl Tetrapeptide-7 (acetate)
	Palmitoyl tetrapeptide-7 is a cosmeceutical peptide that stimulates type I collagen, fibronectin, and hyaluronic acid production in skin.1Formulations containing palmitoyl tetrapeptide-7 have been used in the treatment o...
TP2186	PalMitoyl Tripeptide-1		Others
	PalMitoyl Tripeptide-1 affects the synthesis of collagen, fibronectin and hyaluronic acid in human skin fibroblasts and can be used to prepare anti-aging cosmetics.		Others
T81186	SDGR
	SDGR, a tetrapeptide comprising a serine-aspartic acid-glycine-arginine (Ser-Asp-Gly-Arg) sequence, efficiently impedes cell attachment mediated by fibronectin [1].
T76289	EILEVPST
	EILEVPST, a recombinant human fibronectin-derived low-molecular-weight peptide fragment, promotes cell type-specific α4 integrin-mediated adhesion. It is utilized in thrombogenesis research [1].
T81005	Tetrapeptide-4
	Tetrapeptide-4 is a peptide commonly incorporated into skincare formulations for its anti-aging benefits, which include diminishing wrinkles and fortifying collagen, elastin, and fibronectin [1].
T82359	G-{d-Arg}-GDSP
	G-{d-Arg}-GDSP, an RGD peptide analogue, binds to the adhesion receptor of integrins, inhibiting cellular attachment to fibronectin and osteoclast resorption [1].
TP2186L1	PalMitoyl Tripeptide-1 hydrochloride	PalMitoyl Tripeptide-1 hydrochloride(147732-56-7 Free base)	Others
	PalMitoyl Tripeptide-1 hydrochloride (PalMitoyl Tripeptide-1 hydrochloride (147732-56-7 Free base)) has effects on the synthesis of collagen, fibronectin and hyaluronic acid in human skin fibroblasts, and can be used in ...		Others
T82887	Bifikafusp alfa	L19-IL2
	Bifikafusp alfa (L19-IL2) is an immunotherapeutic fusion protein that combines human L19 antibodies with the cytokine interleukin 2 (IL2), targeting the extra domain B (EDB) of fibronectin with demonstrated anticancer ac...
T75765	GRGDSPK TFA
	GRGDSPK TFA (EMD 56574 TFA) is a peptide containing the Arg-Gly-Asp (RGD) sequence. It acts as a competitive and reversible inhibitor of integrin-fibronectin binding. This compound is utilized in research to elucidate in...
TP1910	CALP1
	Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-...
T83770	Klotho-derived Peptide 1 (56-87) (human) TFA	KP1 (56-87)
	Klotho-derived peptide 1 (KP1) (56-87), a peptide originating from the human Klotho protein, disrupts TGF-β signaling by binding to TGF-β receptor types 1 and 2 (TGFBR1 and TGFBR2; Kds = 1.41 and 14.6 µM, respectively). ...

Compounds

Fibronectin CS1 Peptide acetate

TP1526L1

Synonym:

Target: Others

YRGDS Fibronectin Fragment acetate

TP1530L

Synonym: YRGDS Fibronectin Fragment acetate(134282-68-1 free base)

Target: Others

Fibronectin CS1 Peptide

TP1526

Synonym:

Target:

Fibronectin Type III Connecting Segment Fragment 1-25

Target: TGF-beta/Smad

Palmitoyl Tetrapeptide-7 (acetate)

T36930

Synonym:

Target:

PalMitoyl Tripeptide-1

PalMitoyl Tripeptide-1 hydrochloride

TP2186L1

Synonym: PalMitoyl Tripeptide-1 hydrochloride(147732-56-7 Free base)

Klotho-derived Peptide 1 (56-87) (human) TFA

T83770

Synonym: KP1 (56-87)

Target:

Cat No.	Product Name	Synonyms	Targets
T2S2043	Dracorhodin perchlorate	Dracorhodin perochlorate,Dracohodin perochlorate	Apoptosis , Others
	Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...		Apoptosis , Others
T72798	Ganodermaones B
	Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .
T83392	2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid
	2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, markedly reduces fibronectin levels by 27.66% at a concentration of 10 μM in HK-2 cells subjected to high-glucose and TGF-b1 induction [1].

Natural Products

Dracorhodin perchlorate

T2S2043

Synonym: Dracorhodin perochlorate,Dracohodin perochlorate

Target: Apoptosis, Others

2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid

T83392

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01430	NovoNectin Protein, Human, Recombinant	Human	E. coli
	Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containin...
TMPY-00803	Fibronectin Protein, Human, Recombinant (aa 607-1265, His)	Human	HEK293
	Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPY-02159	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 192 kDa. Accession number: P08648&P05556-1
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPJ-01433	Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated	Human	E. coli
	Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ...
TMPY-02032	FLRT1 Protein, Human, Recombinant (His)	Human	HEK293
	The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1...
TMPY-00176	FNDC4 Protein, Human, Recombinant (mFc)	Human	HEK293
	FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F...
TMPY-05562	Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)	Human	HEK293
	Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His)	Human	Human Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ...
TMPJ-00194	IL-20RB Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-04643	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)	Mouse	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-01608	Decorin Protein, Human, Recombinant (His)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	Human Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-05274	IL-23R Protein, Human, Recombinant (His)	Human	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPK-00994	FNDC1 Protein, Human, Recombinant (His)	Human	E. coli
	Fibronectin type III domain‑containing protein 1 (FNDC1) is a protein that contains a major component of the structural domain of fibronectin.FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, target...
TMPH-00214	SVMP Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Snake venom zinc metalloproteinase that acts on fibrinogen, fibrin, fibronectin (FN1), type I collagen, type IV collagen, integrin alpha-7/beta-1 (ITGA7/ITGB1) and integrin alpha-1/beta-1 (ITGA1/ITGB1). Binds to fibronec...
TMPH-01537	ITGB7 Protein, Human, Recombinant (His)	Human	E. coli
	Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts wi...
TMPJ-00404	EphA4 Protein, Human, Recombinant	Human	Human Cells
	Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and ...
TMPJ-00405	EphA4 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and ...
TMPH-03206	ITGB8 Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b...
TMPJ-00643	TIE2 Protein, Human, Recombinant (aa 23-745, His)	Human	Human Cells
	Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epid...
TMPJ-01227	Irisin Protein, Human/Mouse/Rat, Recombinant (C-His)	Human,Mouse,Rat	Human Cells
	Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene.Human Irisin is synthesized as a 212 amino acid (aa) precursor encoding a type 1 transmembrane pro...
TMPJ-00642	TIE2 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epid...
TMPJ-01226	Irisin Protein, Human/Mouse/Rat, Recombinant (hFc)	Human,Mouse,Rat	Human Cells
	Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene.Human Irisin is synthesized as a 212 amino acid (aa) precursor encoding a type 1 transmembrane pro...
TMPY-04671	MCP-5 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa...
TMPY-03058	SLITL2/VASN Protein, Human, Recombinant (His)	Human	HEK293
	Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular...
TMPJ-00447	MMP-3 Protein, Human, Recombinant (His)	Human	Human Cells
	MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem...
TMPJ-00157	CD82 Protein, Human, Recombinant (hFc)	Human	Human Cells
	CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki...
TMPJ-00216	IL-12B Protein, Human, Recombinant	Human	Human Cells
	Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, a...
TMPJ-00810	ITGA5 Protein, Human, Recombinant (His)	Human	Human Cells
	Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas...
TMPY-04063	CHL1 Protein, Mouse, Recombinant	Mouse	HEK293
	Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsiv...
TMPH-03114	ITGB1 Protein, Pig, Recombinant (His & Myc)	Sus scrofa (Pig)	E. coli
	Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. I...
TMPY-03819	CHL1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsiv...
TMPY-03770	CHL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsiv...
TMPY-01688	CHL1 Protein, Human, Recombinant (His)	Human	HEK293
	Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsiv...
TMPY-04471	APEG1 Protein, Human, Recombinant (His)	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPY-02434	Prolactin Receptor Protein, Rat, Recombinant (His)	Rat	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPJ-00424	EphB2 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. Ephrin r...
TMPY-04100	MMP-26 Protein, Human, Recombinant	Human	E. coli
	MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family me...
TMPY-01566	Prolactin Receptor Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-05038	Decorin Protein, Human, Recombinant	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-00774	Decorin Protein, Human, Recombinant (hFc)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPJ-00403	EphB1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His)	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPY-00155	IL-23R Protein, Rat, Recombinant (His)	Rat	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03008	IL-23R Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03281	IL-23R Protein, Human, Recombinant (hFc)	Human	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-06685	Galectin-1 Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence simil...
------------------------ More ------------------------